Biology Reference
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Figure 4.13 (a) One-zero null hypothesis data: scatter plot of signature
log 10 -tpm pairs (q i , j ,q i , j
), where replicates j and j' are biological replicates taken
at t
0 (i.e., each q is the log of an aggregate tpm derived from two MPSS
replicates) for all signatures i that have one MPSS replicate measurement of
zero tpm counts in either j or j' (or both). Also plotted are equivalent points
for which j and j ' are biological replicates taken at t
=
4h. (b) Standard deviation
of measurement noise s as a function of signal level q for data shown in (a).
(c) Two-zero null hypothesis data: distribution of nonzero signature tpm
values taken from biological replicates taken at t
=
0. Data taken from biological
replicate j where the aggregate tpm measurement in j' was zero and from
j' where the aggregate tpm measurement in j was zero. Also plotted are
equivalent points for which j and j ' are biological replicates taken at t
=
=
4 h.
The dark shaded region is the significant data for p equal to 0.05.
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