Chemistry Reference
In-Depth Information
2,4,5-Trichlorophenol chloroformate 95 is prepared from 94 with triphosgene
and N,N-dimethylaniline in toluene at 80
C [55].
Cl
Cl
Cl
Cl
OH
O
Cl
O
O
(CCl
3
O)
2
CO
Cl
O
DMA, Toluene, 80°C
Cl
Cl
Cl
Cl
Cl
Cl
Cl
Cl
54 %
4 %
94
95
96
N-(Phenoxycarbonyloxy)thiopyridone derivatives 99 are e
cient unimolecular
photochemical sources for the clean generation of phenoxyl radicals. They are pre-
pared by the reaction of lithium phenoxides with phosgene (from triphosgene and
pyridine in a 1:3 molar ratio) [56].
Bu
t
Bu
t
1.
n
-BuLi,Hexane
2.
Triphosgene
, Py
THF
OH
OCOCl
Bu
t
Bu
t
R
R
97
98
SH
O
Bu
t
S
N
OCOO
N
Bu
t
THF, -78 °C
R
99
R = Bu
t
, OMe and Me
Chloroformate 101 of tetrabenzo[a,c,g,i ]fluorenyl-17-methanol 100 was obtained
with triphosgene [57].
O
Cl
OH
O
(CCl
3
O)CO
DMA, CH
2
Cl
2
71 %
100
101
