Biomedical Engineering Reference
In-Depth Information
a
b
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-1
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50 100 150 200 250 300 350 400 450
c
d
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2
0
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-6
1
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0
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-2
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Fig. 7.3 PCA analysis of a set of 1,000 jittered synthetic time series of 512 time samples. ( a )Nine
time series out of 1,000. ( b ) Original raster plot. ( c ) 2D PCA projection. ( d ) 3D PCA projection
two points x and z are close according to the manifold
M
,then f
(
x
)
and f
(
z
)
must
n . To express this regularity constraint in mathematical terms,
also be close in
R
notice that for n
=1
, a Taylor expansion provides the following inequality [ 2 ]
|
f
(
z
)
f
(
x
) |≤
d M (
x, z
) ||∇
f
(
x
) || +
o
(
d M (
x, z
))
,
where
f stands for the gradient of f and d M
is the geodesic distance on the
manifold between points x and z . The notation g
(
z
)=
o
(
d M (
x, z
))
means that
)
d M ( x,z )
g
(
z
as z tends towards x .
In order to obtain an embedding that satisfies the “regularity” constraint,
Laplacian-based methods control the smoothness of f globally by minimizing
0
tends to
M ||∇
f
(
x
) || 2 p
(
x
)
dx , provided that
M ||
) || 2 p
f
(
x
(
x
)
dx
=1
.
(7.3)
The latter condition removes the scaling indeterminacy for the function f .
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