Chemistry Reference
In-Depth Information
Chapter 6
Biomimetic Interfaces of Plasma-
Modified Titanium Alloy
Shuilin Wu a,b and Paul K. Chu b
a
Faculty of Materials Science and Engineering, Hubei University, Wuhan Friendship
Road 368#, Wuchang District, Wuhan, Republic of China
b
Department of Physics and Materials Science, City University of Hong Kong, Tat Chee
Avenue, Kowloon, Hong Kong, Republic of China
paul.chu@cityu.edu.hk
The interfaces between titanium alloy implants and the surrounding
tissues play a critical role for the cells adhesion, proliferation, and
differentiation as well as tissues ingrowth, and thus determining
the good osteointegration. A biomimetic interface aims to mimic
the biological environments of extracellular matrix (ECM) including
surface chemistry and surface topography and thus benefits the
friendly feeling by actin filopodia and consequently, final affinity
recognition by several types of receptors in transmembrane protein,
which directs the subsequent good reaction between cells/tissues
and bone implants. This chapter summarised the recent progress of
interfacial design of titanium alloy implants from the two aspects:
surface structure and surface chemistry of implants by plasma-
based techniques.
 
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