Biomedical Engineering Reference
In-Depth Information
(2002) The protofilament structure of insu-
lin amyloid fibrils. Proc Natl Acad Sci USA
99:9196-9201
26. Lührs T, Ri C, Adrian M, Riek-Loher D,
Bohrmann B, Döbeli H, Schubert D, Riek R
(2005) 3D structure of Alzheimer's amyloid-
b(1-42) fibrils. Proc Natl Acad Sci USA
102:17342-17347
27. Quintas A, Vaz DC, Cardoso I, Saraiva MJM,
Brito RMM (2001) Tetramer dissociation
and monomer partial unfolding precedes
protofibril formation in amyloidogenic
transthyretin variants. J Biol Chem 276:
27207-27213
28. Relini A, Torrassa S, Rolandi R, Ghiozzi A,
Rosano C, Canale C, Bolognesi M, Plakoutsi
G, Bucciantini M, Chiti F, Stefani M (2004)
Monitoring the process of HypF fibrillization
and liposome permeabilization by protofi-
brils. J Mol Biol 338:943-957
29. Lashuel HA, Petre BM, Wall J, Simon M,
Nowak RJ, Walz T, Lansbury PT (2002)
a-Synuclein, especially the Parkinson's disease-
associated mutants, forms pore-like annular
and tubular protofibrils. J Mol Biol 322:
1089-1102
30. Poirier MA, Li H, Macosko J, Cail S, Amzel
M, Ross CA (2002) Huntingtin spheroids
and protofibrils as precursors in polyglutamine
fibrillization. J Biol Chem 277:41032-41037
31. Caughey B, Lansbury PT (2003) Protofibrils,
pores, fibrils and neurodegeneration: sepa-
rating the responsible protein aggregates
from the innocent bystanders. Annu Rev
Neurosci 26:267-298
32. Lin H, Bhatia R, Lal R (2001) Amyloid b
protein forms ion channels: implications for
Alzheimer's disease pathophysiology. FASEB
J 15:2433-2444
33. Bucciantini M, Giannoni E, Chiti F, Baroni
F, Formigli L, Zurdo J, Taddei N, Ramponi
G, Dobson CM, Stefani M (2002) Inherent
toxicity of aggregates implies a common
mechanism for protein misfolding diseases.
Nature 416:507-511
34. Sirangelo I, Malmo C, Iannuzzi C,
Mezzogiorno A, Bianco MR, Papa M, Irace
G (2004) Fibrillogenesis and cytotoxic
activity of the amyloid-forming apomyo-
globin mutant W7FW14F. J Biol Chem
279:13183-13189
35. Ceru S, Kokalj SJ, Rabzelj S, Skarabot M,
Gutierrez-Aguirre I, Kopitar-Jerala N,
Anderluh G, Turk D, Turk V, Zerovnik E
(2008) Size and morphology of toxic
oligomers of amyloidogenic proteins:
a case study of human stefin B. Amyloid
15:47-59
36. O'NuallainB,WetzelR(2002)Conformational
Abs recognizing a generic amyloid fibril
epitope. Proc Natl Acad Sci USA 99:
1485-1490
37. Kayed R, Head E, Thompson JL, McIntire
TM, Milton SC, Cotman CW, Glabe CG
(2003) Common structure of soluble amy-
loid oligomers implies common mechanisms
of pathogenesis. Science 300:486-489
38. Ren P-H, Laucker JE, Kachirskaia I, Heuser
JE, Melki R, Kopito RR (2009) Cytoplasmic
penetration and persistent infection of mam-
malian cells by polyglutamine aggregates.
Nat Cell Biol 11:219-225
39. Chen Y, Kokholyan N (2005) A single disul-
fide bond differentiates aggregation path-
ways of b2-microglobulin. J Mol Biol 354:
473-482
40. Danzer KM, Haasen D, Karow AR, Moussaud
S, Habeck M, Giese A, Kretzschmar H,
Hengerer B, Kostka M (2007) Different
species of a-synuclein oligomers indice cal-
cium influx and seeding. J Neurosci 271:
9220-9232
41. Bravo R, Arimon M, Valle-Delgado JJ,
Garcia R, Durany N, Castel S, Cruz M,
Ventura S, Fernandez-Busquets X (2008)
Sulfated polysaccharides promote the assem-
bly of amyloid b 1-42 peptide into stable fibrils
of reduced cytotoxicity. J Biol Chem 283:
32471-32783
42. Gharibyan AL, Zamotin V, Yanamandra K,
Moskaleva OS, Margulis BA, Kostanyan IA,
Morozova-Roche LA (2007) Lysozyme
amyloid oligomers and fibrils induce cellular
death via different apoptotic/necrotic path-
ways. J Mol Biol 365:1337-13349
43. Novitskaya V, Bocharova OV, Bronstein I,
Baskakov IV (2006) Amyloid fibrils of mam-
malian prion protein are highly toxic to cul-
tured cells and primary neurons. J Biol Chem
281:13828-13836
44. Kayed R, Pensalfini A, Margol L, Sokolov Y,
Sarsoza F, Head E, Hall J, Glabe C (2009)
Annular protofibrils are a structurally and
functionally distinct type of amyloid oli-
gomer. J Biol Chem 284:4230-4237
45. Hirakura Y, Kagan BL (2001) Pore forma-
tion by beta-2-microglobulin: a mechanism
for the pathogenesis of dialysis-associated
amyloidosis. Amyloid 8:94-100
46. Bucciantini M, Calloni G, Chiti F, Formigli
L, Nosi D, Dobson CM, Stefani M (2004)
Pre-fibrillar amyloid protein aggregates share
common features of cytotoxicity. J Biol Chem
279:31374-31382
47. Walsh DM, Selkoe DJ (2004) Oligomers
on the brain, the emerging role of soluble
Search WWH ::




Custom Search