Biomedical Engineering Reference
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References
1. Komatsu M, Ueno T, Waguri S, Uchiyama Y,
Kominami E, Tanaka K (2007) Constitutive
autophagy: vital role in clearance of unfavor-
able proteins in neurons. Cell Death Differ
14:887-894
2. Uchiyama Y, Koike M, Shibata M (2008)
Autophagic neuron death in neonatal brain
ischemia/hypoxia. Autophagy 4:404-408
3. Sarkar S, Ravikumar B, Floto RA, Rubinsztein
DC (2009) Rapamycin and mTOR-indepen-
dent autophagy inducers ameliorate toxicity
of polyglutamine-expanded huntingtin and
related proteinopathies. Cell Death Differ
16:46-56
4. Komatsu M, Waguri S, Chiba T, Murata S,
Iwata J, Tanida I, Ueno T, Koike M, Uchiyama
Y, Kominami E, Tanaka K (2006) Loss of
autophagy in the central nervous system
causes neurodegeneration in mice. Nature
441:880-884
5. Hara T, Nakamura K, Matsui M, Yamamoto
A, Nakahara Y, Suzuki-Migishima R,
Yokoyama M, Mishima K, Saito I, Okano H,
Mizushima N (2006) Suppression of basal
autophagy in neural cells causes neurodegen-
erative disease in mice. Nature 441:885-889
6. Komatsu M, Wang QJ, Holstein GR, Friedrich
VL Jr, Iwata J, Kominami E, Chait BT,
Tanaka K, Yue Z (2007) Essential role for
autophagy protein Atg7 in the maintenance
of axonal homeostasis and the prevention of
axonal degeneration. Proc Natl Acad Sci USA
104:14489-14494
7. Koike M, Shibata M, Waguri S, Yoshimura K,
Tanida I, Kominami E, Gotow T, Peters C,
von Figura K, Mizushima N, Saftig P,
Uchiyama Y (2005) Participation of autophagy
in storage of lysosomes in neurons from
mouse models of neuronal ceroid-lipofuscino-
ses (batten disease). Am J Pathol 167:
1713-1728
8. Cao Y, Espinola JA, Fossale E, Massey AC,
Cuervo AM, MacDonald ME, Cotman SL
(2006) Autophagy is disrupted in a knock-in
mouse model of juvenile neuronal ceroid lipo-
fuscinosis. J Biol Chem 281:20483-20493
9. Kabeya Y, Mizushima N, Ueno T, Yamamoto
A, Kirisako T, Noda T, Kominami E, Ohsumi
Y, Yoshimori T (2000) LC3, a mammalian
homologue of yeast Apg8p, is localized in
autophagosome membranes after processing.
EMBO J 19:5720-5728
10. Tanida I, Minematsu-Ikeguchi N, Ueno T,
Kominami E (2005) Lysosomal turnover, but
not a cellular level, of endogenous LC3 is a
marker for autophagy. Autophagy 1:84-91
11. Bjorkoy G, Lamark T, Brech A, Outzen H,
Perander M, Overvatn A, Stenmark H,
Johansen T (2005) p62/SQSTM1 forms pro-
tein aggregates degraded by autophagy and
has a protective effect on huntingtin-induced
cell death. J Cell Biol 171:603-614
12. Komatsu M, Waguri S, Koike M, Sou YS, Ueno
T, Hara T, Mizushima N, Iwata J, Ezaki J,
Murata S, Hamazaki J, Nishito Y, Iemura S,
Natsume T, Yanagawa T, Uwayama J, Warabi
E, Yoshida H, Ishii T, Kobayashi A, Yamamoto
M, Yue Z, Uchiyama Y, Kominami E, Tanaka K
(2007) Homeostatic levels of p62 control cyto-
plasmic inclusion body formation in autophagy-
deficient mice. Cell 131:1149-1163
13. Hara T, Takamura A, Kishi C, Iemura S,
Natsume T, Guan JL, Mizushima N (2008)
FIP200, a ULK-interacting protein, is
required for autophagosome formation in
mammalian cells. J Cell Biol 181:497-510
14. Ganley IG, Lam DH, Wang J, Ding X, Chen
S, Jiang X (2009) ULK1-ATG13-FIP200
complex mediates mTOR signaling and is
essential for autophagy. J Biol Chem 3:3
15. Jung CH, Jun CB, Ro SH, Kim YM, Otto
NM, Cao J, Kundu M, Kim DH (2009) ULK-
Atg13-FIP200 complexes mediate mTOR
signaling to the autophagy machinery. Mol
Biol Cell 20:1992-2003
16. Hosokawa N, Hara T, Kaizuka T, Kishi C,
Takamura A, Miura Y, Iemura S, Natsume T,
Takehana K, Yamada N, Guan JL, Oshiro N,
Mizushima N (2009) Nutrient-dependent
mTORC1 association with the ULK1-Atg13-
FIP200 complex required for autophagy. Mol
Biol Cell 20:1981-1991
17. Thoreen CC, Kang SA, Chang JW, Liu Q,
Zhang J, Gao Y, Reichling LJ, Sim T, Sabatini
DM, Gray NS (2009) An ATP-competitive
mammalian target of rapamycin inhibitor
reveals
rapamycin-resistant
functions
of
mTORC1. J Biol Chem 284:8023-8032
18. Sarkar S, Rubinsztein DC (2008) Small mol-
ecule enhancers of autophagy for neurode-
generative diseases. Mol Biosyst 4:895-901
19. Ueno T, Ishidoh K, Mineki R, Tanida I,
Murayama K, Kadowaki M, Kominami E
(1999) Autolysosomal membrane-associated
betaine homocysteine methyltransferase.
Limited degradation fragment of a seques-
tered cytosolic enzyme monitoring autophagy.
J Biol Chem 274:15222-15229
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