Biomedical Engineering Reference
In-Depth Information
Fig. 2.34.
Brightness variation depending on the depth of the phantom
emission power and period of ultrasound for the collapse of microcapsules in
vivo.
2.5.5
Conclusion
We can conclude that the microrobotic DDS can be measured and controlled
using ultrasound. Determining the exact location with the 2D-MTI system,
the microrobot can be activated anywhere and at any time with resonant
ultrasound.
Ifthesystemrequiresmuchmorecomplexcontrol,thecurrentmicroro-
botic DDS could provide an intelligent DDS system, with a microcomputer
or a man-machine interface installed within the sensing and control feedback
loop.
This system could form the basis of an intelligent noninvasive in vivo drug
delivery system, although no conventional DDS has an active feedback loop
for measurement and activation drugs. Using this method, any type of drug
can be delivered anywhere in a patient. This technique will play an important
role in medical microrobot systems.
2.6
The Biological Effects of Ultrasound
Ultrasound has been utilized as a source of vibration and cavitation in the
industrial field. The term “sonication” means the use of ultrasound for was-
hing small fine parts of a machine, homogenizing suspensions and emulsions
such as milk, destroying structure, and many other purposes. In the medical
field, the ultrasound scalpel is very useful for soft tissue surgery. Ultraso-
und (shockwave) lithotripsy has become a common therapy for stones in the
urinary tract calculi. In the production process of medicine, ultrasonic ho-
mogenizing and standing wave formation can be used for homogenizing and
particle separation.
