Environmental Engineering Reference
In-Depth Information
table . (Continued)
Critical Properties of nanomaterials
Paradigm
nanoscale
Materials
stewardship
Program
[]
life Cycle
analysis:
nanoRisk
Framework
a
[]
Voluntary
Reporting
scheme
[]
Property
.
Acute.toxicity:
.
.
Administered.orally
•
.
.
Administered.by.inhalation
•
.
.
Administered.cutaneously
•
.
.
Eye.irritation
•
.
Repeated.dose.toxicity.(28.days)
•
.
.Short-term.toxicity,.including.one.or.more.of.the.
following:
•
.
.
•..28-day.inhalation.study.with.full.histopathology,.
over.90-day.observation.period
.
.
•..Single-dose.instillation.study.with.full.
histopathology,.over.a.90-day.observation.period
.
.
•..28-day.repeated-dose.oral.toxicity.test.with.full.
histopathology,.over.a.90-day.observation.period
.
Skin.sensitization/irritation
•
•
.
Skin.penetration,.if.valid.tests.exist
•
.
Genetic.toxicity.tests
•
•
.
.Assessment.of.the.toxicokinetic.behavior.derived.
from.base.set.data.and.other.relevant.information
•
.
.Toxicity.assessment.derived.from.non-animal.test.
methods,.including.
in vitro
.methods.and.Quantitative.
Structure.Activity.Relationships.(QSARs)
•
8..Environmental.hazards:
.
Bacteriological.inhibition
•
.
Acute.aquatic.toxicity.to:
•
•
.
.
•..Fish.(fathead.minnow.or.rainbow.trout)
.
.
•.Invertebrates.(daphnia).—.acute.or.chronic.
depending.on.conditions
.
.
•..Aquatic.plants.(algae)
.
Terrestrial.toxicity,.including.acute.toxicity.to:
•
. . •.Invertebrates.(earthworms)
. . •..Plants
9. Risk management practices:
.
Possibility.of.recycling
•
.
Possibility.of.neutralization.of.unfavorable.effects
•
