The Application of MicroRNAs in Cancer Diagnostics - RNA Interference from Biology to Therapeutics - page 283

and speed. Also, new systems biology approaches which integrate genome-wide
sequencing data obtained at different molecular levels (e.g., genome, transcriptome,
and epigenome) for the clinical sample may help to reveal the complex molecular
mechanisms that regulate cancer development and progression in more depth. An
improved understanding of the fundamental molecular and biological processes
occurring during carcinogenesis could not only provide the basis for development
of new biomarkers, but may also contribute to the future development of new path-
way-targeted therapies.
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