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of impacted genomic functions. Basic fundamental research is needed, not only genotox-
icity studies for DNA structure integrity, but also transcriptomic studies to identify sets
of genes subjected to alterations and dysfunctioning. No doubt the development of the
“omics” technologies will be useful to investigate the mechanisms underlying pollutant
toxicity. Furthermore, they have the potential to provide new high-throughput tools for
the detection of genomic disturbance and pollution fingerprints.
Acknowledgment
The authors warmly thank Mireille Ollivier, CNRS, for a literature survey and help in
providing documentation.
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