Hydrolases in Polymer Chemistry: Chemoenzymatic Approaches to Polymeric Materials - Enzymatic Polymerisation - page 78

Hydrolases in Polymer Chemistry:
Chemoenzymatic Approaches
to Polymeric Materials

Andreas Heise and Anja R.A. Palmans

Abstract Lipases show high activity in the polymerization of a range of monomers
using ring-opening polymerization and polycondensation. The range of polymer
structures from this enzymatic polymerization can be further increased by combi-
nation with chemical methods. This paper reviews the developments of the last 5-8
years in chemoenzymatic strategies towards polymeric materials. Special emphasis
is on the synthesis of polymer architectures like block and graft copolymers and
polymer networks. Moreover, the combination of chemical and enzymatic catalysis
for the synthesis of unique chiral polymers is highlighted.

Keywords Block copolymers · Chirality · Dynamic kinetic resolution · Graft

copolymer · Kinetic resolution · Polymer networks

Contents

1 Introduction .................................................................................... 80

2 Chemoenzymatic Synthesis of Polymer Architectures ...................................... 81

2.1 Crosslinked Structures ................................................................. 81

2.2 Copolymers ............................................................................. 84

2.3 Block Copolymers ..................................................................... 85

2.4 Graft Copolymers ...................................................................... 93

2.5 Branched Structures .................................................................... 95