Biology Reference
In-Depth Information
Table 3.5
Distribution of Kiss1r mRNA based on RT-PCR, in situ hybridization using radioactive probes (ISH) or immunohistochemistry for
β
-galactosidase (
β
-gal)
Medial
septum
Hippo/
DG
Medial
amygdala
Locus
coeruleus
GnRH
neurons
Other
regions References
Species
MBH/ARC
a
POA
RP3V
AHA
DMH
PH
LHA
Human (PCR)
++
+++
+++
++
+
b
[
75
,
76
]
Rhesus monkey
(PCR)
+(M)
++(F)
++(M) +(F)
[
42
,
79
,
80
]
Mouse (PCR)
++
++
+++
+
+
c
[
85
]
Mouse (ISH)
85-95%
[
13
,
100
]
Mouse (β-gal)
-
++
-
-
-
++
-
++
+++
-
+
40-70%
+
d
[
78
,
88
]
Rat (PCR)
+
++
++
+
[
22
,
81
-
84
]
Rat (ISH)
+++
++
++
+++
++
+++
p
+++
+++
+++
77%
+
e
[
20
,
77
]
Sheep (ISH)
p
p
+
78-90%
[
35
,
86
,
87
]
p
Present but not quantifi ed (from reports of
Kiss1r
in GnRH neurons)
a
PCR data is from MBH in humans and ARC in rodents and sheep
b
Other regions include thalamus, substantial nigra, cingulated gyrus
c
Other regions include cerebellum, striatum
d
Other regions include supramammillary nucleus, anteroventralthalamus, habenula; periaqueductal gray
e
Other regions include: zona incerta, olfactory cortex, ventral premammillary, periaqueductal gray
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