Visual Prosthesis Based on Optic Nerve Stimulation with Penetrating Electrode Array - Artificial Sight: Basic Research, Biomedical Engineering, and Clinical Advances - page 187

1 Visual Prosthesis Based on Optic
Nerve Stimulation with Penetrating
Electrode Array
Qiushi Ren 12 , Xinyu Chai 12 , Kaijie Wu 12 , Chuanqing Zhou 12
and C-Sight Group 2
1 Institute for Laser Medicine and Bio-Photonics, College of Life Science and
Technology, Shanghai Jiao-Tong University
2 C-Sight Group: C-Sight Group is a Research Consortium on Visual Prosthesis Funded
by the Chinese Ministry of Science and Technology Under National Key Basic Research
Program (973 Program, 2005CB724300). The principal investigators of the C-Sight
Group include:
1. Qiushi Ren, Ph.D. (Program Chief Scientist), Department of Biomedical Engineering,
Shanghai Jiao-Tong University
2. Li, Xiao-Xin, M.D., Department of Ophthalmology, Beijing University School of
Medicine
3. Liang, Pei-Ji, Ph.D., Department of Biomedical Engineering, Shanghai Jiao-Tong
University
4. Zhu, Yi-Sheng, Ph.D., Department of Biomedical Engineering, Shanghai Jiao-Tong
University
5. Zhuang, Song-Lin, Ph.D., Shanghai University of Science and Technology
6. Zhao Jian-Long, Ph.D., Shanghai Inst. For Micro-System Fabrication Research
of CAS
7. Wang, Jin-Ye, Ph.D., Department of Biomedical Engineering, Shanghai Jiao-Tong
University
Introduction
The successful development and application of cochlear implants in the deaf has
encouraged several research groups to start projects on visual prosthesis for the
blind. The C-Sight (Chinese Project for Sight) is the first multidisciplinary research
project on visual prosthesis in China funded by the Chinese Ministry of Science
and Technology under the National Key Basic Research Program (973 Program,
2005CB724300) and by the Science and Technology Commission of Shanghai
Municipality (STCSM). Thegoal of theC-Sight Project is todevelopan implantable
microelectronic medical device that will restore useful vision to blind patients.
The attempts involved electrical stimulation of primary visual cortex [1-3]
and retina [4-6] have proved that phosphene can be artificially elicited in blind
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