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[102] Hers I, Tavaré JM, Denton RM. The protein kinase C inhibitors bisindolylmaleimide I (GF 109203x) and IX (Ro 31-8220)
are potent inhibitors of glycogen synthase kinase-3 activity. FEBS Lett. 1999; 460: 433-436.
[103] Davies SP, Reddy H, Caivano M, Cohen P. Specificity and mechanism of action of some commonly used protein kinase
inhibitors. Biochem. J. 2000; 351: 95-105.
[104] Coghlan MP, Culbert AA, Cross DA, Corcoran SL, Yates JW, Pearce NJ, Rausch OL, Murphy GJ, Carter PS, Roxbee CL,
Mills D, Brown MJ, Haigh D, Ward RW, Smith DG, Murray KJ, Reith AD, Holder JC. Selective small molecule inhibitors
of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription. Chem. Biol. 2000; 7: 793-803.
[105] Smith DG, Buffet M, Fenwick AE, Haigh D, Ife RJ, Saunders M, Slingsby BP, Stacey R, Ward RW. 3-Anilino-4-
arylmaleimides: potent and selective inhibitors of glycogen synthase kinase-3 (GSK-3). Bioorg. Med. Chem. Lett. 2001;
11: 635-639.
[106] Ruetz S, Fabbro D, Zimmermann J, Meyer T, Gray N. Chemical and biological profile of dual Cdk1 and Cdk2 inhibitors.
Curr. Med. Chem. AntiCanc. Agents. 2003; 3: 1-14.
[107] Olesen PH, Sørensen AR, Ursø B, Kurtzhals P, Bowler AN, Ehrbar U, Hansen BF. Synthesis and in vitro characterization
of 1-(4-aminofurazan-3-yl)-5-dialkylaminomethyl-1H-[1,2,3]triazole-4-carboxylic acid derivatives. A new class of
selective GSK-3 inhibitors. J. Med. Chem. 2003; 46: 3333-3341.
[108] Ding S, Wu TY, Brinker A, Peters EC, Hur W, Gray NS, Schultz, P. G., Synthetic small molecules that control stem cell
fate. Proc. Natl. Acad. Sci. USA, 2003; 100: 7632-7637.
[109] Peat AJ, Garrido D, Boucheron JA, Schweiker SL, Dickerson SH, Wilson JR, Wang TY, Thomson SA, Novel GSK-3
inhibitors with improved cellular activity, Bioorg. Med. Chem. Lett. 2004; 14: 2127-2130.
[110] Dessalew N, Patel DS, Bharatam PV. 3D-QSAR and molecular docking studies n pyrazolopyrimidine derivatives as
glycogen synthase kinase-3beta inhibitors. J. Mol. Graph. Model. 2006; 25: 885-895.
[111] Gadakar P, Phukan S, Dattatreya P, Balaji VN. Pose prediction accuracy in docking studies and enrichment of actives in
the active site of GSK-3beta. J. Chem. Inf. Model. 2007; 47: 1446-1459.
[112] Lather V, Kristam R, Saini JS, Karthikeyan NA, Balaji VN. QSAR Models for Prediction of Glycogen Synthase Kinase-
3beta Inhibitory Activity of Indirubin Derivatives. QSAR Comb. Sci., 2008; 27(6): 718-728.
[113] Dessalew N, Bharatam PV. Investigation of potential glycogen synthase kinase 3 inhibitors using pharmacophore mapping
and virtual screening. Chem. Biol. Drug Des. 2006; 68: 154-165.
[114] Dessalew N, Bharatam PV. Retraction notice to "Colon-specific, mutual azo prodrug of 5-aminosalicylic acid with L-
tryptophan: synthesis, kinetic studies and evaluation of its mitigating effect in trinitrobenzenesulfonic acid-induced colitis
in rats. Bioorg. Med. Chem. 2007; 15: 3728-3736.
[115] Kim HJ, Choo H, Cho YS, No KT, Pae AN. Novel GSK-3beta inhibitors from sequential virtual screening. Bioorg. Med.
Chem. 2008; 16: 636-643.
[116] Gund P. Pharmacophoric pattern searching and receptor mapping, Annu. Rep. Med. Chem., 1977; 4: 299-308.
[117] van Drie JH. Pharmacophore discovery-lessons learned. Curr. Pharm. Des., 2003; 9: 1649-1664.
[118] Engels MF, Thielemans T, Verbinnen D, Tollenaere JP, Verbeeck RJ. CerBeruS: a system supporting the sequential
screening process. J. Chem. Inf. Comput. Sci. 2000; 40: 241-245.
[119] CATALYST 4.11 User Guide, Accelrys, San Diego, CA, USA, 2006.
[120] Rarey M, Kramer B, Lengauer T, Klebe G. A fast flexible docking method using an incremental construction algorithm. J.
Mol. Biol. 1996; 261: 470-489.
[121] Liu T, Lin Y, Wen X, Jorrisen RN, Gilson MK. BindingDB: a web-accessible database of experimentally determined
protein-ligand binding affinities. Nucleic Acids Research. 2007, 35: D198-D201.
[122] Chen X, Lin Y, Gilson M K. The Binding Database: Overview and User's Guide, Biopolymers Nucleic Acid Sci. 2002; 61:
127-141.
[123] Chen X, Lin Y, Liu M, Gilson MK. The Binding Database: data management and interface design. Bioinformatics. 2002;
18: 130-139.
[124] Chen X, Liu M, Gilson MK. BindingDB: A web-accessible molecular recognition database. J. Combi. Chem. High-
Throughput Screen. 2001; 4: 719-725.
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