Chemistry Reference
In-Depth Information
[2] Yankner BA. Mechanisms of neuronal degeneration in Alzheimer's disease, Neuron. 1996; 16, 921-932.
[3] Kang J, Lemaire HG, Unterbeck A, Salbaum JM, Masters CL, Gzeschik KH, Multhaup G, Beyreuther K, Müller-Hill B.
The precursor of Alzheimer's disease amyloid A4 protein resembles a cell-surface receptor, Nature, 1987; 325, 733-736.
[4] Morrison JH, Hof PR, Life and death of neurons in the aging brain. Science, 1997; 278: 412-419
[5] Hardy J, A hundred years of Alzheimer's disease research. Neuron 2006; 52: 3-13.
[6] Selkoe DJ. The cell biology of beta -amyloid precursor protein and presenilin in Alzheimer's disease. Trends Cell Biol
1998; 8: 447-453.
7] Lee SJ, Liyanage U, Bickel PE, Xia W, Lansbury PJ, Kosik KS. A detergent-insoluble membrane compartment contains A
beta in vivo, Nat. Med. 1998; 4: 730-734.
[8] Selkoe, DJ, Schenk D. Alzheimer's disease: molecular understanding predicts amyloid-based therapeutics, Annu. Rev.
Pharmacol. Toxicol. 2003; 43: 545-584
[9] Masters CL, Simm G, Weinman NA, Multhaup G, McDonald BL, Beyreuther K, Amyloid Plaque. Core Protein in
Alzheimer Disease and Down Syndrome, Proc. Natl. Acad. Sci. USA, 1985; 82: 4245-4249.
[10] Grundke-Iqbal I, Iqbal K, Tung YC, Quinlan M, Wisniewski HM, Binder LI. Abnormal phosphorylation of the microtubule-
associated protein tau (tau) in Alzheimer cytoskeletal pathology. Proc. Natl. Acad Sci USA, 1986; 83: 4913-4917.
[11] Grundke-Iqbal I, Iqbal K, Quinlan M, Tung YC, Zaidi MS, Wisniewski HM. Microtubule-associated protein tau. A
component of Alzheimer paired helical filaments. J. Biol. Chem. 1986; 261: 6084-6089.
[12] Iqbal K, Grundke-Iqbal I, Smith AI, George L, Tung YC, Zaidi T. Identification and localization of a τ peptide to paired
helical filaments of Alzheimer disease. Proc. Natl. Acad. Sci. USA, 1989; 86: 5646-5650.
[13] Lee VM, Balin BJ, Otvos LJ, Trojanowski JQ. A major subunit of paired helical filaments and derivatized forms of normal
Tau. Science 1991; 251: 675-678.
[14] Selkoe DJ, Alzheimer's Disease: A Central Role for Amyloid, J. Neuropathol. Exp. Neurol. 1994; 53: 438-447.
[15] Nagy Z, Esiri MM, Jobst KA, Morris JH, King EMF, McDonald B, Litchfield S, Smith A, Barnetson L, Smith AD.
Relative Roles of Plaques and Tangles in the Dementia of Alzheimer's Disease: Correlations Using Three Sets of
Neuropathological Criteria, Dementia 1995; 6, 21-31.
[16] Lovestone S, Reynolds CH. The phosphorylation of tau: a critical stage in neurodevelopment and neurodegenerative
processes. Neuroscience, 1997: 78, 309-324.
[17] Goedert M, Crowther RA, Garner CC. Molecular characterization of microtubule-associated proteins tau and MAP2.
Trends Neurosci. 1991; 14(5):193-199.
[18] Lee VMY, Goedert M, Trojanowski JQ, Neurodegenerative taupathies, Annu. Rev. Neurosci. 2000; 24: 1121-1159.
[19] Rossor NM, Newman S, Frackowiak SR, Lantos P, Kennedy AM. Alzheimer's disease families with amyloid precursor
protein mutations, Ann. N. Y. Acad. Sci. 1993; 695: 198-202.
[20] Campion D, Flaman MJ, Brice A, Hannequin D, Dubois B. Martin C. et al., Mutations of the presenilin I gene in families
with early-onset Alzheimer's disease, Hum. Mol. Genet. 1995; 4: 2373-2377.
[21] Cruts M, Hendriks L, van Broeckhoven C. The presenilin genes: a new family involved in Alzheimer's disease pathology.
Hum. Mol. Genet. 1996; 5: 1449-1455.
[22] Levy-Lahad E, Wasco W, Poorkaj P, Romano DM, Oshima J, Pettingell WH, Yu CE, Jondro PD, Schmidt SD, Wang K. et
al., Candidate gene for the Chromosome 1 familial Alzheimer's disease locus, Science, 1995; 269: 973-977.
[23] Rogaev EI, Sherrington R, Rogaeva EA, Levesque G, Ikeda M, Liang Y, Chi H, Lin C, Holman K, Tsuda T, et al.,
Familial Alzheimer's disease in kindred with missens mutations in a gene on chromosome 1 related to the Alzheimer's
disease type 3 gene. Nature, 1995; 376: 775-778.
[24] Ezquerra M, Carnero C, Blesa R, Oliva R. A Novel Presenilin 1 Mutation (Leu166Arg) Associated With Early-Onset
Alzheimer Disease, Arch. Neurol., 2000; 57: 485-488.
[25] Selkoe DJ. Translating cell biology into therapeutic advances in Alzheimer's disease. Nature, 1999; 399: A23-A31.
[26] Takashima A, Honda T, Yasutake K, Michel G, Murayama O, Murayama M, Ishiguro K, Yamaguchi H, Activation of tau
protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in
hippocampal neurons. Neurosci. Res. 1998; 31: 317-323.
[27] Balaraman Y, Limaye AR, Levey AI, Srinivasan S, Glycogen synthase kinase 3beta and Alzheimer's disease:
pathophysiological and therapeutic significance. Cell. Mol. Life Sci., 2006; 63:1226-1235.
[28] Borchelt DR, Ratovitski T, van Lare J, Lee MK, Gonzales V, Jenkins NA, Copeland NG, Price DL, Sisodia SS.
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor
proteins. Neuron 1997; 19: 939-945.
[29]
Loo TD, Copani A, Pike JC, Whittemore RE, Walencewicz AJ, Cotman CW. Apoptosis is induced by B-amyloid in
cultured central nervous system neurons. Proc. Natl. Acad. Sci. USA, 1993; 90: 7951-7955.
Search WWH ::




Custom Search