Biology Reference
In-Depth Information
Chapter 30
Association Analysis Between DNA Markers
and Number of Functional Teats in Italian
Large White Pigs
S. Dall'Olio, L. Fontanesi, L. Tognazzi, L. Buttazzoni, M. Gallo, and V. Russo
Abstract The aim of this work was to study the association between five single-
nucleotide polymorphisms (SNPs), each in one of five genes (
CTSL
,
EPOR
,
ESR2
,
GPX5
, and
STAT5B
), and functional teat number (FTNUM). Each marker was
genotyped in at least 940 Italian Large White sows. All SNPs segregated in the
analyzed breed with minor allele frequencies ranging from 0.18 (
CTSL
and
EPOR
)
to 0.40 (
ESR2
). The genotyped sows were categorized into two classes based on
their FTNUM: FTNUM equal to 14 (59% of the samples) and FTNUM greater than
14 (41%). Differences in allele frequencies between the two classes were statisti-
cally significant (
P
0.01) for the
GPX5
polymorphism.
<
Keywords Polymorphisms • Functional teat number • Sows • Italian Large White
Abbreviations
ANAS National Association of Pig Breeders
FTNUM Functional teat number
ITLW
Italian Large White pig breed
MAF
Minor allele frequency
MAS
Marker assisted selection
QTL
Quantitative trait loci
SNP
Single nucleotide polymorphism
UTR
Untranslated region
S. Dall'Olio (
*
) • L. Fontanesi • L. Tognazzi • V. Russo
Dipartimento di Protezione e Valorizzazione Agroalimentare, Universit` degli Studi di Bologna,
Bologna, Italy
e-mail:
stefania.dallolio@unibo.it
L. Buttazzoni • M. Gallo
ANAS, Associazione Nazionale Allevatori Suini, Via Lazzaro Spallanzani 4/6, 00161 Roma, Italy
