Biology Reference
In-Depth Information
Chapter 19
Canine Chronic Kidney Disease: Retrospective
Study of a 10-Year Period of Clinical Activity
G. Guidi, C. Rossini, C. Cinelli, V. Meucci, and I. Lippi
Abstract Chronic kidney disease (CKD) is a progressive, pathological disease
with a higher prevalence in geriatric patients. The aim of the present study was to
estimate the prevalence of dogs affected by CKD at the Department of Veterinary
Clinics over a 10-year period of clinical activity, according to gender, age, breed,
and IRIS stage. Males showed a prevalence of 60.17%, while females showed
a prevalence of 39.82%; 28.40% of dogs were younger than 6 years, 42.12% were
between 6 and 10 years, and 29.46% were older than 10 years. Mixed breed patients
showed a prevalence of 31.38%, followed by Boxer (9.36%), German shepherd
(7.76%), and setter (5.42%). The prevalence of CKD was 24.25% in IRIS 2, 52.97%
in IRIS 3, and 22.76 in IRIS 4. The results showed that CKD represents a more
frequent reason for consultation in canine patients than in the past. It is not clear
whether the high prevalence of CKD is due to an actual increase in the disease or an
increased frequency of early diagnosis.
Keywords Chronic kidney disease Dog IRIS Prevalence
19.1
Introduction
Chronic kidney disease (CKD) is a complex clinical syndrome that represents the
end point of a progressive pathological process of one or more sections of the
nephron (glomerule, tubule, interstice, and vessel) (Brown
2007
). The small num-
ber of epidemiologic studies concerning the prevalence of CKD in dogs reflects the
situation in the United States. CKD was prevalent in 0.5-1.5% of the dogs
G. Guidi (
*
) C. Rossini C. Cinelli V. Meucci I. Lippi
Department of Veterinary Clinics, Veterinary Teaching Hospital, University of Pisa, Pisa, Italy
e-mail:
guidi@vet.unipi.it
