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Table 3.
qEEG results in experimental and control group
Parameter
Control
CRF
p
-value
MDF 1-25 Hz
10.65
±
0.71
10.11
±
0.86
<
0.001
MDF 6-14 Hz
8.20
±
0.37
8.09
±
0.42
0.062
Spectral Entropy
4.52
±
0.065
4.48
±
0.081
0.0022
δ
relative power [0.75-4 Hz]
0.234
±
0.062
0.274
±
0.081 0.00102
δ
1
relative power [0.75-2 Hz]
0.136
±
0.042
0.162
±
0.056 0.00112
δ
2
relative power [2-4 Hz]
0.0985
±
0.023
0.112
±
0.027 0.00233
θ
relative power [4-8 Hz]
0.145
±
0.281 0.156
±
0.0242
0.0101
α
relative power [8-12 Hz]
0.197
±
0.069
0.191
±
0.072
n.s.
β
relative power [15-25 Hz]
<
0.001
0.376
±
0.052
0.340
±
0.055
γ
relative power [25-40Hz]
0.097
±
0.031
0.101
±
0.032
n.s.
Sample Entropy
0.796
±
0.36
0.916
±
0.35
0.0414
The last layer is given by the probablitity of belonging to experimental or
control groups. Therefore, different epochs of the EEG trace were classified by
the network in different categories. 20 examples were automatically presented to
the ANN (10 experimental and 10 controls) until these were correctly classified
between experimental and control groups, and rest of cases were presented to
test the ANN.
2.5 Statistics
The statistical contrasts (table 3) were performed in each case using the
t
-
Student or Mann-Whitney test, depending on whether or not compliance with
the assumption of normality in the data. Correlations were assessed using Pear-
son correlation. The
α
significance level was set to 0
.
05, although values under
0
.
1 will be reflected. The statistics were calculated using open-source program
R
[10].
3R su s
3.1 EEG Results
Visual analysis:
Visual analysis of EEG, reported by an expert (physician spe-
cialist in clinical neurophysiology), reported minor alterations: 13 traces were
normal, 3 of low voltage, 1 with presence of
δ
bursts during hyperventilation
(normal variant).
qEEG:
We found significant differences in qEEG between control and experimen-
tal groups in almost all studied parameters. The experimental group presented
reduced MDF, MDF
6
−
14
Hz
, spectral entropy and
β
power, and increased
δ
and
θ
power and sample entropy (see table 3).
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