Biology Reference
In-Depth Information
73
Let the distance between genetic markers A and B be denoted by D. Then a
similar calculation as before gives:
= c µ
2
(L
-
D)
3
/ 6 .
Therefore, the co-transduction frequency is simply:
c.f. = [A+B+] / [A+] = (1- D/L)
3
.
which is independent of c or µ (Wu, 1966). As long as the measurement of
[A+] and [A+B+] are carried out in the same experiment, there is no need to
determine c nor µ . This result is plotted in Fig. 3-5, quite different from the
straight line shown in Fig. 3-2.
Figure 3-5.
Biological relevant relation of co-transduction frequency and distance
between genetic markers in generalized random transduction.
