Biology Reference
In-Depth Information
110
Other methods for more accurate numerical integration of non-linear
ordinary differential equations are commonly used, e.g. Taylor-series, Euler,
Runge-Kutta, etc. (see, for example, Gerald, 1978).
INHIBITORS
There are two simply types of enzyme inhibitors: competitive and non-
competitive (Dixon and Webb, 1964). Other more complicated types are
also possible. In the case of the fully competitive inhibitor, we have:
and
where I denotes the inhibitor. If we make the similar assumptions as in the
case of simple enzyme kinetics, i.e. d[ES]/dt = 0, d[EI]/dt = 0, [S] = [S]
0
,
and [I] = [I]
0
, we have:
and
so that
