Biology Reference
In-Depth Information
1
2
3
ESR1
FOXA1
SCUBE2
ERBB4
BCL2
ERBB3
AR
GATA3
CA12
SLC39A6
XBP1
MYB
TFF3
TFF1
KRT18
CCND1
1
2
3
ESR1
FOXA1
SCUBE2
ERBB4
BCL2
ERBB3
AR
GATA3
CA12
XBP1
MYB
TFF3
TFF1
CCND1
RARA
KRT5
KRT7
KLF5
KRT16
PROM1
CDH3
LMO4
EGFR
FABP7
CRYAB
YBX1
FOXC1
RARA
KRT5
KRT7
KLF5
KRT16
PROM1
CDH3
LMO4
EGFR
FABP7
CRYAB
YBX1
FOXC1
ERBB2
GRB7
STARD3
PERLD1
AURKA
CCNB2
BUB1
FOXM1
CCNB1
CDKN3
MCM6
CCNE2
MCM2
CCNA2
MCM10
CCNE1
MCM3
PTTG1
BIRC5
TOP2A
MYBL2
PCNA
LMNB1
MKI67
CKS1B
TK1
TYMS
E2F1
ERBB2
GRB7
STARD3
PERLD1
AURKA
CCNB2
BUB1
FOXM1
CCNB1
CDKN3
MCM6
CCNE2
MCM2
CCNA2
MCM10
CCNE1
MCM3
PTTG1
BIRC5
TOP2A
MYBL2
PCNA
LMNB1
MKI67
CKS1B
TK1
TYMS
E2F1
DPT
RECK
DCN
TGFB3
TGFBR2
IGF1
SPARCL1
DPT
RECK
DCN
TGFB3
TGFBR2
IGF1
SPARCL1
PLAU
MMP11
CTSK
PLAUR
CTSB
MMP2
MMP13
TIMP3
MMP1
LAMB1
TIMP2
COL11A1
COL5A2
COL10A1
COL5A1
COL6A3
COL6A2
COL1A2
COL3A1
COL6A1
PLAU
MMP11
CTSK
PLAUR
CTSB
MMP2
MMP13
TIMP3
MMP1
LAMB1
TIMP2
COL11A1
COL5A2
COL10A1
COL5A1
COL12A1
COL6A3
COL6A2
COL1A2
COL3A1
COL6A1
STAT1
HLA-G
HLA-F
HLA-C
HLA-B
HLA-DRA
HLA-DMA
HLA-DQB1
HLA-DPA1
HLA-E
HLA-DMB
MX1
IFIT3
IRF1
IFITM1
GZMA
CD38
IFIT5
STAT1
HLA-G
HLA-F
HLA-C
HLA-B
HLA-DRA
HLA-DMA
HLA-DQB1
HLA-DPA1
HLA-E
HLA-DMB
MX1
IFIT3
IRF1
IFITM1
GZMA
CD38
IFIT5
0
5
10
15
0
5
10
15
censored
event
censored
event
Fig. 2.
Coexpression module heat maps for the (a) NKI and (b) EMC datasets.
The expression level from high to low is coded with a red-white-blue color gradient.
receptor signaling, ERBB2 amplification, and proliferation (ESR1, ERBB2,
and AURKA) discriminate well between the three subgroups. The mod-
ules for invasion and immune response (PLAU and STAT1) do not show
a distinct pattern.
