Raman Spectroscopy of Ocular Tissue - Emerging Raman Applications and Techniques in Biomedical and Pharmaceutical Fields - page 299

Fig. 12.11. a Schematics of fundus camera-interfaced RRS instrument for mea-
surement of integral MP concentrations in human clinical studies; b computer mon-
itor display showing raw Raman spectrum obtained after single measurement ( left
panel ) and processed, scaled, spectrum obtained after subtraction of fluorescence
background ( right panel )

pathology. In Fig. 12.12, MP levels are shown as an example for ∼ 100 healthy

volunteer subjects, ranging in age from 20 to 50 years. Each circle repre-

sents an MP concentration of a subject's retina, as determined by the Raman
intensity of the MP carotenoid response. As seen in Fig. 12.12, the MP con-
centration can vary strongly between subjects at any age. Low MP levels of
subjects are likely to correlate with their risk for vision problems later in life.

∼