Biomedical Engineering Reference
In-Depth Information
Fig. 10.11.
Raman (
A
) and SERS (
B
) spectra of different penicillin samples in
fermentation broths [69]. Copyright by the Royal Society of Chemistry
10.5 Future Opportunities and Challenges
Raman spectroscopy has its main strength in the combination of a fairly high
chemical selectivity and a true remote sensing capability. In comparison, NIR
has been used extensively in the manufacturing industry due to its ruggedness
and simplicity with respect to interfacing of probes to process vessels. How-
ever, due to fairly poor spectral selectivity it has to be paired with multivariate
data evaluation and is thus sometimes considered as a 'black box' technique.
Mid-IR, on the other hand, offers a high selectivity and is also well established
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