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AUTHORS' CONTRIBUTIONS
Raul O. Gonzalez performed the preparation and structural characterization of ARC
(size and Z potential, electronic microscopy), as well as cytotoxicity, cell transit, and
immunization schemes. Leticia H. Higa grew the archaea strains, isolated the TPL,
and grew the J-774 and Vero cells. Also contributed to the cytotoxicity, cell transit,
and immunization schemes together with Raul O. Gonzalez. Marcos Bilen performed
the DNA sequencing, C + G content, and finger print analysis. Irma Morelli per-
formed the biochemical tests. Romina A. Cutrullis performed ELISA measurements.
Diana I. Roncaglia performed the ESI-MS spectra and analysis. Patricia B. Petray and
Ricardo S. Corral designed and developed the immunization protocols, participated to
the discussion of the results and manuscript preparation, and provided minor financial
support. Maria Jose Morilla coordinated the performance experiments and analysis of
experimental results. Eder L. Romero coordinated the experiments, wrote the manu-
script, and provided main financial support. All authors read and approved the final
manuscript.
ACKNOWLEDGMENTS
This work was financially supported by Secretaria de Investigaciones, Universidad
Nacional de Quilmes and the Consejo Nacional de Investigaciones Científicas y
Técnicas (CONICET, Argentina). Maria Jose Morilla, Patricia B. Petray, Ricardo S.
Corral, and Eder L. Romero are members of the Researcher Career Programme from
CONICET. Leticia H. Higa and Romina A. Cutrullis are fellows from CONICET.
 
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