Low Calorie Nonnutritive Sweeteners - Sweeteners: Nutritional Aspects, Applications, and Production Technology - page 107

table 4.4 Chromatographic techniques for Multianalyte analysis in Functional Foods
ACS-K a , ASP b ,
SAC c

Soft drinks,
juice,
tomato
sauce,
strawberry
sweets

FiA with online
monolithic
element

Water (0.4 M in NaCl, 5 × 10 −3
M NaClo 4 )
(pH = 9)

Quaternary
amine ion
exchanger
monolithic
column

0.9 μg/mL 0.09% 97.6%-

103.4% and
3-600 μg/
mL

Jiménez et
al. 2009

ACS-K, ASP,
SAC, vanillin,
sorbic acid,
benzoic acid

Cola drinks,
instant-
powder
drinks

HPLC-uV ACN-Ammonium acetate buffer

(pH = 4)

YMC-oDS
Pack AM
(5 μm × 250
mm × 4 mm
i.D.)

0.2-3.1 μg/g 1.0%-

2.2%

99%-101%
and N/A

Demiralay
et al. 2006

ACS-K, SAC,
CYC d

Gum iC-uV 300 mg/L Sodium carbonate Dionex AS4A

Separator
column

N/A 1.1% 99.8%-

102.5%
0.0262 mg/mL
-0.0022 mg/
mL

Biemer et al.
1989

DuL e , ACS-K,
SAC,
preservatives,
antioxidants

Soy sauce,
sugared
fruits, dried
roast beef

ion-paired LC-uV ACN-aqueous a-hydroxy-iso

butyric acid solution (pH = 4.5)
containing
hexadecyltrimethylammonium
bromide

Stainless-steel
Shoko 5C 18
column (5 μm ×
25 mm × 4.6
mm i.D.)

0.5 μg/g N/A 81.9%-

89.64% and
N/A

Chen et al.
1995

ACS-K, SAC,
ASP,
antioxidants,
preservatives

Beverages,
low joule
jam

MEKC-uV Sodium tetraborate solution

(pH = 9.5) with Na cholate,
dodecyl sulfate-10% ACN or
isopropanol or MeoH

Fused silica
capillary (60
cm × 75 μm
i.D.)

N/A N/A 98.9%-

100.86%
and N/A

Boyce 1999

SAC, ASP,
ACS-K,
sorbic acid,
benzoic acid,
caffeine,
theobromine,
theophylline

Cola drinks,
preserved
fruits,
tablets,
fermented
milk, fruit
juice

iC-uV Aqueous NaH 2 Po 4

(pH = 8.20) -4% (v/v) ACN

iC-A3
Shim-Pac
(5 μm × 150
mm × 4.6 mm
i.D.)

20 ng/mL 1.5% 85%-104%

and N/A

Chen et al.
2001

SAC, ASP,
ACS-K, CYC,
citric acid

Drinks,
powdered
tabletop
sweeteners

iC-uV-ELCD Na 2 Co 3 solution Dionex ionPac

AS4A-SC
(250 mm ×
4 mm i.D.)

0.26 μg/mL 0.84% 93%-107%

and 2-100
mg/mL

Chen et al.
1997

( continued )