c-MycERTAM Transgene Silencing in a Genetically Modified Human Neural Stem Cell Line Implanted into MCAo Rodent Brain - Genetic Engineering: Recent Developments in Applications - page 83

Table 1. c-mycER TAM transcript copy number and number of CTX0E03 cells calculated in the grafted rat brain
sections at 1- and 4-weeks post-implantation.
transgene Methylation Analysis
Direct modification of the DNA by methylation is an epigenetic mechanism to
downregulate or silence gene expression. Using bisulfite sequencing, the methylation