Biology Reference
In-Depth Information
c-MycertAM transgene
silencing in a Genetically
Modified Human Neural
McAo rodent brain
Lara Stevanato, Randolph L. Corteling, Paul Stroemer,
Andrew Hope, Julie Heward, Erik A. Miljan and John D. Sinden
AbstrAct
Background
The human neural stem cell line CTX0E03 was developed for the cell based
treatment of chronic stroke disability. Derived from fetal cortical brain tis-
sue, CTX0E03 is a clonal cell line that contains a single copy of the c-my-
cER
TAM
transgene delivered by retroviral infection. Under the conditional
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