Environmental Engineering Reference
In-Depth Information
Table 1 Criteria for assessing strength of the methods of toxicity studies on chlorpyrifos and its oxon
Strength of methods
1
2
3
4
5
Description of the
experimental and
procedures
Inadequately
described
or incorrect
Critical information
on methods
missing
Critical information on
methods and procedures
provided
Procedures described
so that the study
could be replicated
or spirit of GLP
Guideline study or
complete detailed
protocol or full GLP
QA/QC
None
Some QC (e.g.,
exposures
measured once)
More QC (e.g., exposures
measured on a regular
basis)
Robust QA/QC
Full QA/QC
Transparency of data
Critical data
not
provided
Summary data only
Summary data with
variance characterized
Key raw data
provided
All raw data provided
Concentrations tested
Only 1 conc.
tested
2 concs. tested
3 concs. Tested or fi eld
study >3 sites
4 concs. tested
5 concs. tested
Descriptors from
Klimisch et al. ( 1997 )
Not assignable
Not reliable
With restriction
Without restrictions
 
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