Chemistry Reference
In-Depth Information
Refer to the structures numbered 1 to 6 in Figure 3.25. In each case
select the form of the drug that predominates in human plasma at
pH 7.4:
(a)
Q3.2
Mono-cation
(b)
Di-cation
(c)
Mono-anion
(d)
Di-anion
(e)
Neutral molecule
O
C
2
H
5
1.
H
2
N
N
C
2
H
5
O
H
O
C
2
H
5
N
2.
O
N
C
2
H
5
O
H
O
3.
C
4
H
9
N
H
N
O
H
OH
H
O
N
Pr
i
O
H
2
N
4.
CH
3
CH
2
OH
5.
O
O
6.
H
O
O
CH
3
Figure 3.25
Structures of drugs.