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(d)
When novobiocin was mixed with 5% Dextrose Injection,
the solution became cloudy. Account for this observation.
OH
H
OH
N
O
O
O
O
CH 3
CH 3
H 3 C
CH 3 O
O
OH
O
O
NH 2
Figure 8.27
The structure of novobiocin.
Explain each of the following observations. Your answer should
include appropriate chemical formulae.
(a)
Q8.2
Penicillin suspensions are supplied as dried granules and are
reconstituted by the pharmacist immediately prior to use.
(b)
Solutions
of
adrenaline
(epinephrine)
become
pink
on
exposure to sunlight.
(c)
Samples of aspirin tablets invariably smell of vinegar.
(d)
The vasoconstrictor peptide angiotensin II has a very short
half-life within the body.
(Answers to problems can be found on pp. 264-266.)
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