Effect of Taurine Feeding on Bone Mineral Density and Bone Markers in Rats - Advances in Experimental Medicine and Biology - page 52

Table 6.4 Serum calcium and phosphorus of rats fed experimental diets
Variables Control Taurine Signi fi cance

Ca (mg/dl) 10.34 ± 0.16 1 9.71 ± 0.30 NS 2

P (mg/dl) 7.04 ± 0.21 7.92 ± 0.51

1 Mean ± SD
2 NS not significantly different at p < 0.05

Table 6.5 Urinary calcium and phosphorus excretion of rats fed experimental diets
Variables Control Taurine Signi fi cance

Ca (mg/day) 0.18 ± 0.07 1 0.08 ± 0.03 **

P (mg/day) 20.56 ± 8.05 15.97 ± 9.96 NS 2

** p < 0.01
1 Mean ± SD
2 NS not significantly different at p < 0.05

Table 6.6 Creatinine, DPD, and cross-link value of rats fed experimental diets
Variables Control Taurine Signi fi cance

Creatinine (mM) 2.96 ± 1.01 1 4.60 ± 2.06 NS 2

DPD (nM) 599.80 ± 239.91 872.01 ± 286.45

Cross-link value (nM/mM) 200.60 ± 31.98 189.56 ± 46.27

1 Mean ± SD
2 NS not significantly different at p < 0.05

6.3.3 Urine Calcium, Phosphorus, Deoxypyridinoline,

Creatinine, and Cross-Link Value

The levels of urinary calcium excretion were 0.18 ± 0.07 mg/day in the control group
and 0.08 ± 0.03 mg/day in the taurine group. The urinary calcium excretion of tau-
rine group was significantly lower than in control group. However, urinary phos-
phorus excretion was not significantly different (Table 6.5 ).
Cross-link values were 200.60 ± 31.98 and 189.56 ± 46.27 (nM/mM) for the con-
trol and taurine groups, respectively. Although urinary cross-link value was gener-
ally higher in the control group than in the taurine group, the difference was not
statistically significant (Table 6.6 ).

6.3.4 Bone Markers

Table 6.7 showed the serum ALP and osteocalcin concentration of experimental
rats. The concentrations of serum ALP were 278.0 ± 45.4 IU/L in the control group
and 260.1 ± 36.4 IU/L in the taurine group. And the concentrations of serum