Taurine Enhances the Sexual Response and Mating Ability in Aged Male Rats - Advances in Experimental Medicine and Biology - page 332

But there is no detailed information on the relation of taurine and penile NO. Our
studies showed that the pensile NOS and NO were increased in aged rats by taurine
administration, which indicated that sexual enhancement may be partly attributed to
the elevated effect of taurine on penile NOS and NO levels. It has been reported that
androgens can mediate the erectile response in the rat penis by stimulating the
expression of NOS, thus maintaining an adequate supply of NO (Reilly et al. 1997 ) ,
which is in agreement with our results.

32.5 Conclusion

In summary, the present study demonstrated that taurine supplement could increase
sexual response and function; stimulate the secretion of GnRH, LH, and T; and
elevate penis NOS and NO level in aged rats. The results implied that taurine can
enhance the sexual response and mating ability in aged male rats by increasing the
level of testosterone and NO, but the exact mechanism needs to be further
investigated.

Acknowledgements This work was supported by the National Natural Science Foundation of
China (Grant No. 31001042), the Doctor Initial Foundation of Liaoning Province (Grant No.
20081065), and the Program for Shenyang Agricultural University Excellent Talents.

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