Biology Reference
In-Depth Information
Table 31.4 Serum calcium and phosphorus concentrations of rats fed experimental diets
Variables
Control
Arg
Tau
Arg + Tau
Ca (mg/dl)
9.41 ± 0.39 1, a, 2
9.50 ± 0.16 a
9.59 ± 0.30 a
9.44 ± 0.30 a
P (mg/dl)
6.34 ± 0.86 a
6.60 ± 0.42 a
6.36 ± 0.29 a
6.98 ± 0.76 a
1 Mean ± SD
2 Values with different superscripts within the row are significantly different at p < 0.05 by Duncan's
multiple range test
Table 31.5 Urinary calcium and phosphorus excretion of rats fed experimental diets
Variables
Control
Arg
Tau
Arg + Tau
Ca (mg/day)
0.38 ± 0.14 1, a, 2
0.35 ± 0.06 a
0.36 ± 0.15 a
0.36 ± 0.11 a
P (mg/day)
17.48 ± 4.39 a
18.33 ± 2.28 a
19.55 ± 3.09 a
19.51 ± 3.31 a
1 Mean ± SD
2 Values with different superscripts within the row are significantly different at p < 0.05 by Duncan's
multiple range test
Table 31.6 Serum ALP and osteocalcin concentration of rats fed experimental diets
Variables
Control
Arg
Tau
Arg + Tau
ALP ( m g/l)
50.7 ± 11.0 1, a, 2
57.7 ± 18.4 a
61.4 ± 18.3 a
59.0 ± 10.7 a
Osteocalcin (ng/ml)
30.14 ± 3.80 a
31.29 ± 4.72 a
32.57 ± 6.92 a
28.25 ± 5.06 a
1 Mean ± SD
2 Values with different superscripts within the row are significantly different at p < 0.05 by Duncan's
multiple range test
was lower in the arginine-supplemented group than in the control group. No
significant differences in calcium excretion were observed. Urinary excretion of
phosphate was greater in the taurine- or arginine-supplemented group than in the
un-supplemented group, but the difference was not significant. Fasting urinary
phosphate excretion was similar in all groups, too. Urinary calcium and phosphate
excretion were nearly identical in all study groups.
31.3.4
Bone Markers
Serum concentrations of ALP and osteocalcin, a marker of bone formation, were not
significantly different among groups (Table 31.6 ). Urinary bone resorption markers,
cross-link value, decreased among experimental groups, but the difference was not
signi fi cant (Table 31.7 ). Urine DPD and cross-link value were lower in the Arg + Tau-
supplemented groups than in the control group and Tau and Arg + Tau groups lower
in the cross-link value than in the Arg group among supplemented groups, but the
difference was not significant. Choi and Seo ( 2006 ) reported that taurine supplemen-
tation increased the femur BMD, and decreased urinary calcium excretion in male
rats. They also found that taurine supplementation signi fi cantly reduced concentrations
of not only DPD and cross-link value. Hip fractures are the most costly of all fracture
types, resulting in significant mortality, morbidity, functional consequences, and
 
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