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Fig. 28.2
Effect of
TauT
deficiency on cell proliferation. Cell numbers were counted using a
hemocytometer for a period of 9 days (
left
). The pace of cell migration is shown on the right. These
results demonstrate that
TauT
de fi ciency inhibits the cells' ability to proliferate
control and TauT-deficient cells were placed into a medium with soft agar, and
colonies were counted after 2 weeks. RNAi directed against
TauT
resulted in a
significant reduction (about 65%) in colony formation of 293 cells in comparison
to control (Fig.
28.3
).
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