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Table 26.2 Content of three monoam ine neurotransmitters in the brain of mice administered with As or As and taurine for 60 days
Cerebrum Cerebellum
NE DA 5-HT NE DA 5-HT
Control 6 169.90 ± 34.40 153.54 ± 24.79 78.67 ± 28.90 113.38 ± 16.36 27.18 ± 7.31 89.05 ± 10.60
4 ppm 6 37.57 ± 9.36 a 62.68 ± 18.08 a 57.73 ± 15.75 a 1.88 ± 0.56 a 4.44 ± 0.30 a 39.35 ± 8.62 a
4 ppm + Taurine 6 74.01 ± 15.73 b 135.47 ± 13.93 b 67.58 ± 8.81 37.75 ± 6.98 b 12.54 ± 0.89 b 61.41 ± 14.09 b
Values are mean ± SD as ng/g of tissue (wet weight). NE norepinephrine, DA dopamine, 5-HT serotonin. Different from control group, a P < 0.05; Different
from 4 ppm group, b P < 0.05
Groups
n
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