Biology Reference
In-Depth Information
21.5
Conclusion
In conclusion, the present study demonstrated that taurine could inhibit the injury
induced by ISO by increasing myocardial negative inotropic effect and antioxidant
ability, decreasing the hypertrophic response to isoproterenol and protecting the
integrity of myocardial ultrastructure, decreasing myocardial leak of CK-MB.
Acknowledgements This study was supported by a grant from the Education Department of
Liaoning Province, China.
References
Adams JE 3rd, Abendschein DR, Jaffe AS (1993) Biochemical markers of myocardial injury. Is
MB creatine kinase the choice for the 1990s? Circulation 88:750-763
Allard ML, Jeejeebhoy KN, Sole MJ (2006) The management of conditioned nutritional require-
ments in heart failure. Heart Fail Rev 1:75-82
Azuma M, Takahashi K, Fukuda T, Ohyabu Y, Yamamoto I, Kim S, Iwao H, Schaffer SW, Azuma
J (2000) Taurine attenuates hypertrophy induced by angiotensin II in cultured neonatal rat
cardiac myocytes. Eur J Pharmacol 403:181-188
Balligand JL (1999) Regulation of cardiac beta-adrenergic response by nitric oxide. Cardiovasc
Res 43:607-620
Calderone A, Thaik CM, Takahashi N, Chang DF, Colucci WS (1998) Nitricoxide, atrial natri-
uretic peptide, and cyclic GMP inhibit the growth-promoting effects of norepinephrine in car-
diac myocytes and fibroblasts. J Clin Invest 101:812-818
Chang L, Xu J, Yu F, Zhao J, Tang X, Tang C (2004) Taurine protected myocardial mitochondria
injury induced by hyperhomocysteinemia in rats. Amino Acids 27:37-48
Chattopadhyay A, Biswas S, Bandyopadhyay D, Sarkar C, Datta AG (2003) Effect of isoprotere-
nol on lipid peroxidation and antioxidant enzymes of myocardial tissue of mice and protection
by quinidine. Mol Cell Biochem 245:43-49
Gan XL, Hei ZQ, Huang HQ, Chen LX, Li SR, Cai J (2006) Effect of Astragalus membranaceus
injection on the activity of the intestinal mucosal mast cells after hemorrhagic shock-reperfu-
sion in rats. Chin Med J 119:1892-1898
Grazyna S, Hinrik S, Michael S, Yvonne BJ, James PM (1999) Altered phosphorylation of sarco-
plasmic reticulum contributes to the diminished contractile response to isoproterenol in hyper-
trophied rat hearts. Eur J Physiol 439:1-10
Hamaguchi T, Azuma J, Schaffer S (1991) Interaction of taurine with methionine: inhibition of
myocardial phospholipid methyltransferase. J Cardiovasc Pharmacol 18:224-230
Hare JM, Givertz MM, Creager MA, Colucci WS (1998) Increased sensitivity to nitric oxide syn-
thase inhibition in patients with heart failure: potentiation of beta-adrenergic inotropic respon-
siveness. Circulation 97:161-166
Hill JA, Olson EN (2008) Cardiac plasticity. N Engl J Med 358:1370-1380
Huxtable R, Bressler R (1974) Taurine concentrations in congestive heart failure. Science
184:1187-1188
Ito T, Kimura Y, Uozumi Y, Takai M, Muraoka S, Matsuda T, Ueki K, Yoshiyama M, Ikawa M,
Okabe M, Schaffer SW, Fujio Y, Azuma J (2008) Taurine depletion caused by knocking out the
taurine transporter gene leads to cardiomyopathy with cardiac atrophy. J Mol Cell Cardiol
44:927-937
Itoh K, Minakawa M, Ono Y, Tsushima K, Fukui K, Fukuda I (2008) Role of oxidative stress in
hypertrophied myoblasts stimulated by isoproterenol. Gen Thorac Cardiovasc Surg 56:170-176
Search WWH ::




Custom Search