Biology Reference
In-Depth Information
0.9
4
0.8
0.7
Liver
Plasma
3
0.6
0.5
2
0.4
0.3
1
0.2
0.1
0
0
Control
NAC
TAU
TTAU
APAP
NAC +
APAP
TAU +
APAP
TTAU +
APAP
Fig. 20.3
The effects of NAC, TAU, and TTAU on liver and plasma GSSG levels of rats treated with
a hepatotoxic (800 mg/kg i.p.) dose of APAP. Differences were significant from control at *
p
< 0.05
and **
p
< 0.01 and from APAP at
†
p
<0.05 and
††
p
<0.01. Values are shown as mean ± SEM for
n
= 6
100
35
Liver
Plasma
90
30
80
25
70
60
20
50
15
40
30
10
20
5
10
0
0
Control
NAC
TAU
TTAU
APAP
NAC +
APAP
TAU +
APAP
TTAU +
APAP
Fig. 20.4
The effects of NAC, TAU, and TTAU on the liver and plasma GSH/GSSG ratios of rats
treated with a hepatotoxic (800 mg/kg i.p.) dose of APAP. Differences were significant from con-
trol at *
p
< 0.05, **
p
< 0.01, and ***
p
< 0.001 and from APAP at
†
p
<0.05,
††
p
<0.01, and
†††
p
< 0.001.
Values are shown as mean ± SEM for
n
= 6
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