Positive Correlation Between Serum Taurine and Adiponectin Levels in High-Fat Diet-Induced Obesity Rats - Advances in Experimental Medicine and Biology - page 103

Table 11.2 Final body weight, organ weight, and adipose tissue weight
Variables N HF HFT

Final BW 535.3 ± 24.0 a 568.4 ± 12.3 541.4 ± 8.3

Relative liver weight (g/100 g BW) 2.7 ± 0.1 2.6 ± 0.1 2.4 ± 0.1

Relative epididymal fat weight (g/100 g BW) 2.2 ± 0.1* ,b 3.0 ± 0.1** 3.1 ± 0.2**

Relative retroperitoneal fat weight (g/100 g BW) 2.4 ± 0.3* 3.6 ± 0.2** 3.6 ± 0.1**

a Mean ± SE
b Values with different superscripts (* and **) within the row are significantly different at p < 0.05
by Duncan's multiple range test

11.2.3 Statistical Analysis

All analyses were performed using SPSS 17.0 program. Each value was expressed
as the mean ± SE. Data were analyzed for significant difference by one-way analysis
of variance followed by Duncan's multiple range tests at a p < 0.05. The correlation
between serum taurine and adipokine levels was analyzed using Spearman's corre-
lation coef fi cient.

11.3 Results and Discussion

11.3.1 Final Body Weight, Organ Weight, and Adipose Tissue

Weight

After 8 weeks, there was no significant difference in final body weight among three
groups (Table 11.2 ). The adipose tissue weights (E-fat and R-fat) of HF group and
HFT group were significantly higher compared to N group. However, there was no
significant difference in the relative liver weight among three groups.

11.3.2 Serum Lipid Pro fi les

Serum lipid profiles are shown in Table 11.3 . The level of serum TG was significantly
lower in N group compared to other groups. The level of serum TC was significantly
lower in HFT group compared to other groups. Taurine supplementation may have
the effect of decreasing the level of serum TC. The previous study reported that vari-
ous amounts of taurine supplementation in rats fed a high-cholesterol diet
significantly decreased serum total cholesterol in a dose-dependent manner
(Yokogoshi et al . 1999 ) .