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Figure 6.2.
Influence of mass width on the elimination of matrix components.
Source
: Ref. [56], Figure 4,
p. 64. Reproduced with permission of Elsevier.
analyzer. These hybrid instruments combine the attributes of QqQmodes for quantitative
analysis and the sensitivity of LIT scan modes such as enhanced product ion scan mode,
time-delayed fragmentation, andMS
3
for the con
rmation of analytes or characterization
of unknowns [93]. The use of third quadrupole (Q3) as a LIT with axial ion ejection
signi
cantly improved ion trap performance by enhancing full scan sensitivity in both
precursor and product ion scan modes, while maintaining complete QqQ operational
modes, that is, MRM mode and precursor and constant neutral loss scanning.
