Agriculture Reference
In-Depth Information
Table 4.3. List of Common PFC Compounds That Can Migrate into Food Samples with
Their Corresponding Q1 and Q3 Transitions Used in LC-MS/MS Analysis
Q1
Mass
(amu)
Q3
Mass
(amu)
PFC
Formula
Abbreviation
Perfluorobutanoic acid
CF
3
(CF
2
)
2
COOH
PFBA
213
169
Perfluoropentanoic acid
CF
3
(CF
2
)
3
COOH
PFPA
263
219
Per
uoro-
n
-hexanoic acid
CF
3
(CF
2
)
4
COOH
PFHxA (C6)
313
269/119
Peruoro-
n
-heptanoic acid
CF
3
(CF
2
)
5
COOH
PFHpA (C7)
363
319/169
Peruoro-
n
-octanoic acid
CF
3
(CF
2
)
6
COOH
PFOA (C8)
413
369/169
Per
uoro-
n
-nonanoic acid
CF
3
(CF
2
)
7
COOH
PFNA (C9)
463
419/219
Per
uoro-
n
-decanoic acid
CF
3
(CF
2
)
8
COOH
PFDA (C10)
513
469/219
Peruoro-
n
-undecanoic acid CF
3
(CF
2
)
9
COOH
PFUnDA (C11)
563
519/269
Peruoro-
n
-dodecanoic acid CF
3
(CF
2
)
10
COOH
PFDoDA (C12)
613
569/319
Peruoro-
n
-tridecanoic acid
CF
3
(CF
2
)
11
COOH
PFTriDA (C13)
663
619/319
Peruoro-
n
-tetradecanoic
acid
CF
3
(CF
2
)
12
COOH
PFTeDA (C14)
713
669/319
Perfluorobutanesulfonic acid CF
3
(CF
2
)
3
SO
3
H
PFBS (S4)
299
80/99
Perfluorohexanesulfonic
acid
CF
3
(CF
2
)
5
SO
3
H
PFHxS (S6)
399
80/99
Peruoro-
n
-heptanesulfonic
acid
CF
3
(CF
2
)
6
SO
3
H
PFHpS (S7)
449
80/99
Perfluorooctanesulfonic acid CF
3
(CF
2
)
7
SO
3
H
PFOS (S8)
499
80/99
Perfluorooctane sulfonamide CF
3
(CF
2
)
6
SO
2
NH
2
PFOSA (S8)
498
78/478
N
-Methylperuoro-1-
octanesulfonamide
CF
3
(CF
2
)
7
SO
2
NHCH
3
N
-MeFOSA
512
169
N
-Ethylperuoro-1-
octanesulfonamide
CF
3
(CF
2
)
7
SO
2
NHC
2
H
5
N
-EtFOSA
526
169
2-(
N
-Methylperuoro-1-
octanesulfonamido)-
ethanol
CF
3
(CF
2
)
7
SO
2
N
CH
3
(C
2
H
4
OH)
N
-MeFOSE
616
59
2-(
N
-Ethylper
uoro-1-octa-
nesulfonamido)-ethanol
CF
3
(CF
2
)
7
SO
2
NC
2
H
5
(C
2
H
4
OH)
N
-EtFOSE
630
59
International Agency for Research on Cancer (IARC) classi
ed azo-dyes as potential
carcinogenic substances. One of the
rst methods used to detect Sudan dyes was
reversed-phase chromatography with APCI ionization in positive mode [55,56]. Most
methods used to detect Sudan dyes are based on LC separation, with MS detection
recently replacing UV detection due to the decrease in the analysis time. Initial LC
-
MS/MS methods were based on APCI and used a simple solvent extraction followed
by filtration to detect Sudan dyes I-IV in chili powder and tomato-based products and
were capable of detecting these dye contaminants at low part per billion levels [55].
These methods screened for only
57] or
ESI [58]. However, Sudan dyes are among a series of dyes that are used in textile
five or fewer dyes by either APCI [55
-