Biomedical Engineering Reference
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remodeling under mechanical conditions (Figure 20.6). It can be concluded that a relatively good
agreement was achieved between the simulation result and the clinical bone density distribution
after implant placement.
20.5 ConCluSIonS
The study involving numerical simulations presented in this chapter was intended to demonstrate how
bone remodeling computational methods can contribute to a great extent to the field of dental bio-
mechanics, including orthodontics and prosthodontics. To assess the biomechanical response from
orthodontic loading and implantation, the existing FE method has proven to be an effective way to
capture the geometrical and material complexities involved. However, bone is a metabolically active
tissue capable of forming its structure and material properties via the process of bone remodeling.
Simulations of bone remodeling can be employed in the investigation of bone biological responses.
Remodeling numerical techniques have the potential to create specific tools to help dentists in their pre-
operational planning to estimate the effectiveness of operational practices as well as assist bioengineers
in their implant design process to optimize solutions for the improvement of an implant's longevity.
Lastly, it should be pointed out that although the present mathematical algorithm has the ability
to predict alveolar bone response through bone remodeling, more substantial biological modeling
algorithms should be introduced into the computer simulation. New methods should be developed
that consider further biomechanical and mechanobiological influences. The gap between biological
theory and computational biomechanics communities should be minimized in the future.
aCknowledgmentS
This work was supported by the National Natural Science Foundation of China (Nos. 10925208,
11120101001, 11202017), the Beijing Natural Science Foundation (7133245), Young Scholars for the
Doctoral Program of the Ministry of Education of China (20121102120039), and the 111 Project
( B130 03).
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