Foot–Ankle–Knee Model for Foot Orthosis - Computational Biomechanics of the Musculoskeletal System - page 150

long-term therapeutic effects and clinical effectiveness of laterally wedged insoles could not be
fully realized through this study. However, the predicted joint loading distribution suggested an
influence on the morphology of the regional cartilage (Koo, Rylander, and Andriacchi, 2011), which
has a strong correlation with joint degeneration.
12.4 ConCluSIonS
Our FE predictions furnished necessary information on the distributions of joint internal loading, that
could not be achieved from gait analysis techniques alone. The finding that laterally wedged orthoses
redistributed the knee internal loadings may contribute to medial knee OA rehabilitation. Besides
exploring joint biomechanical responses to interventions, designing foot orthoses that improve the
joint loading environment should be a primary goal. With the implementation of parametric analy-
ses, any features of the foot orthosis could be altered through FE simulation. Therefore, this foot-
ankle-knee model will also provide scientific fundamentals for designing optimal foot orthoses.
aCknowledgmentS
This study is supported by grants from the National Natural Science Foundation of China (11272273,
11120101001) and the Research Grant Council of Hong Kong (PolyU 532611E).
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