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Figure 9
(a) The energy and free energy of interaction between calbindin and lysozyme at
pH ¼ 4 for a protein model with fixed charges (dashed lines) and one with
charge regulation (solid lines). The amino-acid model is used and the salt
concentration is 5 mM. (b) The variation of net charge of calbindin and
lysozyme as a function of their separation. The simulations are based on the
amino-acid model (pH ¼ 4, salt concentration ¼ 5 mM)
9.4.4 Bridging Attraction with Polyelectrolytes
The adsorption of a polyelectrolyte to an aggregate is a necessary, but not
sufficient, condition to attain a modulation of the free energy. It actually has to
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