Biology Reference
In-Depth Information
population
n
NMR
nuclear magnetic resonance
ODD
oxygen-dependent degradation domain
PAD
predonated autologous blood
PAI
plasminogen activator inhibitor
PEG
polyethylene glycol
polyA
polyadenylation
PRCA
pure red cell aplasia
pVHL
vonHippel-Lindau protein
recombinant
r
rHuEPO
recombinant human erythropoietin
rHuGH
recombinant human growth hormone
rHuIFN
recombinant human interferon
RT-PCR
reverse transcription polymerase chain reaction
SC
subcutaneous, subcutaneously
SCF
stem cell factor
SCFR
receptor for stem cell factor
SDS-PAGE
sodium dodecyl sulfate-polyacrilamide gel electrophoresis
SFFV
spleen focus-forming virus
SHIP
SH2-containing inositol-5-phosphatase
SOCS-1
supressor of cytokine-signaling-1
STAT
signal transduction and activator of transcription
TfR
receptor for transferrin
TGF
transforming growth factor
time at which the maximum concentration is observed
T max
TNF
tumor necrosis factor
volume of distribution (generic term)
V d
volume of distribution at steady state (estimated after single
dose administration after distribution processes have been
completed). In the case of a 2-compartment system, it is the
sum of the central and peripheral volume s of distribution
V ss
volume of distribution associated with the terminal phase (not
very practical)
V z
theoretical maximum rate of elimination associated with the
non-linear pathway
V max
VEGF
vascular endothelial growth factor
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