Biology Reference
In-Depth Information
22 Maxwell PH, Osmond MK, Pugh CW, Heryet A, Nicholls LG, Tan CC, Doe BG, Ferguson DJ,
Johnson MH, Ratcliffe PJ (1993) Identification of the renal erythropoietin-producing cells using
transgenic mice.
Kidney Int
44: 1149-1162
23Magnanti M, Gandini O, Giuliani L, Gazzaniga P, Marti HH, Gradilone A, Frati L, Agliano AM,
Gassmann M (2001) Erythropoietin expression in primary rat Sertoli and peritubular myoid cells.
Blood
98: 2872-2874
24 Semenza GL, Wang GL (1992) A nuclear factor induced by hypoxia via
de novo
protein synthe-
sis binds to the human erythropoietin gene enhancer at a site required for transcriptional activa-
tion.
Mol Cell Biol
12: 5447-5454
25 Pugh CW, Tan CC, Jones RW, Ratcliffe PJ (1991) Functional analysis of an oxygen-regulated tran-
scriptional enhancer lying 3' to the mouse erythropoietin gene.
Proc Natl Acad Sci USA
88:
10553-10557
26 Bunn HF, Poyton RO (1996) Oxygen sensing and molecular adaptation to hypoxia.
Physiol Rev
76: 839-885
27 Galson DL, Tsuchiya T, Tendler DS, Huang LE, Ren Y, Ogura T, Bunn HF (1995) The orphan
receptor hepatic nuclear factor 4 functions as a transcriptional activator for tissue-specific and
hypoxia-specific erythropoietin gene expression and is antagonized by EAR3/COUP-TF1.
Mol
Cell Biol
15:2135-2144
28Ebert BL, Bunn HF (1998) Regulation of transcription by hypoxia requires a multiprotein com-
plex that includes hypoxia-inducible factor 1, an adjacent transcription factor, and p300/CREB
binding protein.
Mol Cell Biol
18: 4089-4096
29 Goldberg MA, Gaut CC, Bunn HF (1991) Erythropoietin mRNA levels are governed by both the
rate of gene transcription and post-transcriptional events.
Blood
77:271-277
30 Miranda CE, Scaro JL, Buys MC, Torrejon I, Martin B, Guerra L (1998) Urinary elimination of
erythropoietin in patients under treatment with cytostatics drugs.
Acta Physiol Pharmacol Ther
Latinoam
48: 207-210
31 Chapel S, Veng-Pedersen P, Hohl RJ, Schmidt RL, McGuire EM, Widness JA (2001) Changes in
erythropoietin pharmacokinetics following busulfan-induced bone marrow ablation in sheep:
Evidence for bone marrow as a major erythropoietin elimination pathway.
J Pharmacol Exp Ther
298: 820-824
32 Chapel SH, Veng-Pedersen P, Schmidt RL, Widness JA (2001) Receptor-based model accounts for
phlebotomy-induced changes in erythropoietin pharmacokinetics.
Exp Hematol
29: 425-431
33 Marmont AM (1997) Erythropoietin: Biochemical characteristics, biologic effects, indications and
results of use in hematology.
Tumori
83: S3-S15
34 Broudy VC, Lin N, Brice M, Nakamoto B, Papayannopoulou T (1991) Erythropoietin receptor
characteristics on primary human erythroid cells.
Blood
77: 2583-2590
35 Constantinescu SN, Keren T, Socolovsky M, Nam H, Henis YI, Lodish HF (2001) Ligand-inde-
pendent oligomerization of cell-surface erythropoietin receptor is mediated by the transmembrane
domain.
Proc Natl Acad Sci USA
98: 4379-4384
36 Chen C, Sytkowski AJ (2001) Erythropoietin activates two distinct signaling pathways required
for the initiation and the elongation of c-myc.
J Biol Chem
276: 38518-38526
37 von Lindern M, Parren-van Amelsvoort M, van Dijk T, Deiner E, van den AE, Emst-de Vries S,
Willems P, Beug H, Lowenberg B (2000) Protein kinase C alpha controls erythropoietin receptor
signaling.
J Biol Chem
275: 34719-34727
38 Frank SJ (2002) Receptor dimerization in GH and erythropoietin action - it takes two to tango,
but how?
Endocrinology
143: 2-10
39Cheung JY, Miller BA (2001) Molecular mechanisms of erythropoietin signaling.
Nephron
87:
215-222
40 Koury MJ, Bondurant MC (1990) Erythropoietin retards DNA breakdown and prevents pro-
grammed death in erythroid progenitor cells.
Science
248: 378-381
41 Koury MJ, Bondurant MC (1990) Control of red cell production: The roles of programmed cell
death (apoptosis) and erythropoietin.
Transfusion
30: 673-674
42 Spivak JL, Pham T, Isaacs M, Hankins WD (1991) Erythropoietin is both a mitogen and a survival
factor.
Blood
77: 1228-1233
43 Krantz SB (1991) Erythropoietin.
Blood
77: 419-434
44 Udupa KB, Reissmann KR (1980) Stimulation of erythroblast formation in suspension cultures of
murine marrow by a factor in normal mouse serum, and its relationship to erythropoietin.
Exp
Hematol
8: 1106-1113
