Database Reference
In-Depth Information
AS S D
AS SUSC * Nat DR
S allele TR
=
=
0.00066
Trans AS
=
Infected Vector * S allele TR
Conversions
AA Total
=
AA IMMUNE
+
AA INF
+
AA SUSC
AS Total
=
AS IMMUNE
+
AS INF
+
AS SUSC
INFECTED
=
AA INF
+
AS INF
+
SS INF
Percent Infected
=
INFECTED/Total People
SS Total
=
SS IMMUNE
+
SS INF
+
SS SUSC
TOTAL IMMUNE
=
AA IMMUNE
+
AS IMMUNE
+
SS IMMUNE
TOTAL SUSC
=
AA SUSC
+
AS SUSC
+
SS SUSC
Genetic Model
AA births
A FREQ
∧
2 * Total People * BR
=
AA FREQ
=
AA Total/Total People
AS births
=
2*A FREQ * S FREQ * Total People * BR
AS FREQ
=
AS Total/Total People
A alleles
=
AA Total * 2
+
AS Total
A FREQ
=
A alleles/Total Alleles
BR
0.03969
SS births
=
S FREQ
∧
2 * Total People * BR
=
SS FREQ
=
SS Total/Total People
S alleles
=
SS Total * 2
+
AS Total
S FREQ
S alleles/Total Alleles
Total Alleles
=
=
A alleles
+
S alleles
Total People
=
AS Total
+
SS Total
+
AA Total
Normal Blood (AA) Malaria Infection
AA IMMUNE(t)
=
AA IMMUNE(t
−
dt)
+
(AA RECOV
−
AA IMM LOSS
−
AA IM D) * dt
INIT AA IMMUNE
=
1
INFLOWS:
AA RECOV
=
AA INF * RECOV R
OUTFLOWS:
AA IMM LOSS
=
AA IMMUNE * Immunity Loss
AA IM D
=
AA IMMUNE * Nat DR
AA INF(t)
=
AA INF(t
−
dt)
+
(AA INFECT
−
AA RECOV
−
AA I D) * dt
INIT AA INF
=
36
INFLOWS:
AA INFECT
=
AA SUSC*Trans AA * INF LAG
OUTFLOWS:
AA RECOV
=
AA INF * RECOV R
AA I D
=
AA INF * INF DR
