Information Technology Reference
In-Depth Information
￿
￿
￿
CFD simulations of fl uid fl ow: (a) below the paddle in
the USP dissolution apparatus at 50 rpm; and (b) in the
USP dissolution apparatus with a compact of 8.5 mm
height situated at the base of the vessel (reprinted from
McCarthy et al., 2003; with permission from Springer)
Figure 7.9
tangential components of velocity increased linearly with increase in
paddle rotational speed from 25 to 150 rpm. Application of CFD provided
an insight into the three-dimensional mixing route throughout the paddle
apparatus, which has not been possible to achieve with velocimetry
measurements. Path-lines of fl uid mixing from a plane 0.5 mm above the
Search WWH ::




Custom Search