Immune Reconstitution of the CD4 T-Cell Compartment in HIV Infection - Cellular Aspects of HIV Infection - page 389

Figure 20.1. Kinetics and mechanisms of CD4 T-cell reconstitution after HAART initiation
during late disease. (A) An initial increase, usually rapid and large, represents redistribution of
memory CD4 T cells, and is followed by a second, slow but steady increase that re¯ects regeneration
of naive CD4 T cells. The slopes are calculated from data published in Autran et al., 1997 and Li
et al., 1998. (B) The slopes of CD4 increase over the long term depend on the magnitude of the viral
load reduction (calculated from Renaud et al., 1999).