Information Technology Reference
In-Depth Information
record, the sequence alignments in mFASTA format, or a text file containing the
accessions and descriptions of all CD records.
11. Frequently Asked Questions
x Cn3D [http://www.ncbi.nih.gov/Structure/CN3D/cn3dfaq.shtml]
x VAST searches [http://www.ncbi.nih.gov/Structure/VAST/vastsearch_faq.html]
x CDD [http://www.ncbi.nlm.nih.gov/Structure/cdd/cdd_help.shtml]
References
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Wang Y, Anderson JB, Chen J, Geer LY, He S, Hurwitz DI, Liebert CA, Madej T, Marchler GH,
Marchler- Bauer A, et al. MMDB: Entrez's 3D-structure database. Nucleic Acids Res 30:249-252;
2002. (PubMed)
[2]
Wang Y, Geer LY, Chappey C, Kans JA, Bryant SH. Cn3D: sequence and structure views for
Entrez.
[3]
Madej T, Gibrat J-F, Bryant SH. Threading a database of protein cores. Proteins 23:356-369; 1995.
(PubMed)
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Gibrat J-F, Madej T, Bryant SH. Surprising similarities in structure comparison. Curr Opin Struct
Biol 6:377-385; 1996. (PubMed)
[5]
Marchler-Bauer A, Panchenko AR, Shoemaker BA, Thiessen PA, Geer LY, Bryant SH. CDD: a
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Acids Res 30:281-283; 2002. (PubMed)
[6]
Westbrook J, Feng Z, Jain S, Bhat TN, Thanki N, Ravichandran V, Gilliland GL, Bluhm W,
Weissig H,Greer DS, et al. The Protein Data Bank: unifying the archive. Nucleic Acids Res 30:245-
248; 2002. (PubMed) [7. Ohkawa H, Ostell J, Bryant S. MMDB: an ASN.1 specification for
macromolecular structure. Proc Int Conf Intell Syst Mol Biol 3:259-267; 1995. (PubMed)
[8]
Bateman A, Birney E, Cerruti L, Durbin R, Etwiller L, Eddy SR, Griffiths-Jones S, Howe KL,
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[9]
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Genome Res 10:1643-1647; 2000. (PubMed)
Appendix 1: Accession numbers
MMDB records have several types of Accession numbers associated with them,
representing the following data types:
x Each MMDB record has at least three Accession numbers: the PDB code of the
corresponding PDB record (e.g., 1CYO, 1B8G); a unique MMDB-ID (e.g., 645,
12342); and a gi number for each protein chain. A new MMDB-ID is assigned
whenever PDB updates either the sequence or coordinates of a structure record,
even if the PDB code is retained.
x If an MMDB record contains more than one polypeptide or nucleotide chain, each
chain in the MMDB record is assigned an Accession number in Entrez Protein or
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