Chemistry Reference
In-Depth Information
Table 15.3 Clinical Trials with Probiotics in Term Infants (Nutritional Intervention During the First year of life)
Duration of
Intervention
Probiotic
Target group
Main ooutcome
ref.
Lactobacillus casei
CrL431 and
Biidobacterium lactis
bb-12
12 months
119 infants with cow's
milk allergy
supplementation does not accelerate cow's
milk tolerance
Hol et al.
268
B. longum
bb536 +
L. rhamnosus
LPr or
L. paracasei
st11 + gos/
scfos
4 months
284 healthy infants
equivalent weight gain in all groups
Chouraqui et
al.
269
L. rhamnosus
gg
7 months (start 4-6
weeks before
expected delivery)
94 pregnant women/
infants at risk
no reduction in incidence of ad nor altered
severity, increased rate of recurrent episodes
of wheezing bronchitis
kopp et al.
270
L. plantarum
and fos
7 days
31 healthy infants
Colonization of
L. plantarum
, increased
bacterial diversity and gram-positives,
decreased gram-negatives
Panigrahi et
al.
271
B. longum
and Lgg
6 months
37 infants
increased biidobacteria, decreased
enterobacteriaceae and
Bacteroides-
prevotella
Mah et al.
177
L. acidophilus
LaVri-a1
0-6 months
178 infants at high risk
Colonization of lactobacilli
no reduction of ad, increased senzitation to
allergens until 12 months, no inluence on
foXP3 expression, no inluence on innate
immune response, but effect on vaccine
responses
taylor et al.
272-275
B. longum
bb536
(combination with gos/
lcfos)
0-7 months
138 infants without
risk
no difference in growth, reduced constipation
Puccio et al.
229
four probiotic strains
(combination with gos)
0-6 months (start
during pregnancy)
925 infants at high risk
reduction of incidence atopic eczema
kukkonen et
al.
176
